NEW CRYSTALLINE FORMS OF SALT OF MESYLATE 2,3-DIMETHYL-8-(2,6-DIMETHYLBENZYLAMINO)-K-HYDROXYETHYL-IMIDASO[1,2-a]PYRIDINE-6-CARBOXAMIDE, METHODS OF THEIR PREPARATION, PHARMACEUTICAL AGENT, WHICH CONTAINS THEM, THEIR APPLICATION AND METHOD OF TREATMENT Russian patent published in 2009 - IPC C07D471/04 A61K31/437 A61P1/04 A61P11/06 A61P11/08 

Abstract RU 2376306 C2

FIELD: medicine.

SUBSTANCE: present invention is related to new crystalline forms of salt of mesylate2,3-dimethyl-8-(2,6-dimethylbenzylamino)-N-hydroxyethyl-imidaso[1,2-a]pyridine-6-carboxamide and to their mixture. Besides the present invention is also related to methods of their preparation, application and pharmaceutical composition for inhibition of gastric acid secretion, which contains them. Production of new salt of 2,3-dimethyl-8-(2,6-dimethylbenzylamino)-N-hydroxyethyl-imidaso[1,2-a]pyridine-6-carboxamide and its crystalline forms for production of medicinal agent for use in treatment or prophylaxis of gastrointestinal disorders such as gastritis, gastric ulcer, duodenal ulcer, peptic ulcerous diseases, reflux-esophagitis, Zollinger-Ellison syndrome, ulcerogenic adenomas of pancreas, acute bleeding from upper compartments of gastrointestinal tract.

EFFECT: wider area of compounds application.

33 cl, 1 tbl, 12 dwg, 8 ex

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RU 2 376 306 C2

Authors

Lill'Ekuist Lars

Lindkvist Marija

Nordberg Peter

Pettersson Ursula

Sebkhatu Tesfai

Dates

2009-12-20Published

2004-12-16Filed