CONJUGATE FOR IMMUNISATION AND VACCINATION AND METHOD FOR IMPROVING IMMUNOGENICITY Russian patent published in 2010 - IPC A61K39/385 A61P37/00 

Abstract RU 2378015 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine and immunology and concerns a conjugate for immunisation and vaccination and method for improving immunogenicity. Substance of the invention involves said conjugate for immunisation and vaccination representing an immunogen covalently bonded with a high-molecular carrier that is acidic peptidoglycane of molecular weight 1200-40000 KDa, and having the mass ratio of glucose and uronic acids 1:2-4.

EFFECT: advantage of the invention consists in improved immunogenicity 10-100 times higher, that in turn allows reducing immunogen doses in 10-100 times to achieve the same effect.

6 cl, 6 ex, 3 tbl

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RU 2 378 015 C2

Authors

Ataullakhanov Ravshan Inojatovich

Mel'Nikova Tat'Jana Mikhajlovna

Pichugin Aleksej Vasil'Evich

Khaitov Rakhim Musaevich

Dates

2010-01-10Published

2008-04-02Filed