THIOMORPHOLINE COMPOUND AND METHOD FOR MAKING THEREOF Russian patent published in 2010 - IPC C07D417/04 C07D401/04 A61K31/541 A61P1/08 A61P11/14 A61P13/00 A61P25/28 A61P29/00 A61P37/08 

Abstract RU 2379305 C2

FIELD: medicine.

SUBSTANCE: there is described thiomorpholine compound presented by formula (I) wherein the ring A represents benzene ring; the ring B represents benzene ring; R1 represents hydrogen atom, R2 represents C1-6-alkyl group; R3a and R3b are identical or different, each representing hydrogen atom or C1-6-alkyl group, and n represents an integer equal to 2, or its pharmaceutically acceptable salt. There is also described method for making the compound of formula (1), a pharmaceutical composition and application of the compound of formula (1) for making a medical product used for treatment and prevention of the disease chosen from inflammation, allergic diseases, pain, migraine, neuralgia, itch, cough, central nervous system diseases, alimentary organ diseases, nausea, vomiting and urological disorders.

EFFECT: compounds exhibits affinity to neurokinine-1 receptor.

6 cl, 4 tbl, 16 ex

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RU 2 379 305 C2

Authors

Takakhasi Masami

Jamanaka Takesi

Mijake Tsutomu

Dates

2010-01-20Published

2006-09-01Filed