FIELD: chemistry.
SUBSTANCE: invention relates to novel derivatives of benzene sulphonamide of formula (I), tautomeric and stereoisomeric forms and physiologically acceptable salts thereof: where X is O, S; R1 is H, halogen; R2 is H, halogen; halogen; R3 is NO2, CN; R4 is: ,
where R71 is H; R72 is H; Z1 is -[CH2]P-, where p = 2.
EFFECT: compounds have antagonistic activity towards CCR3, which enables for their use in making medicinal agents.
13 cl, 1 tbl, 3 ex
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Authors
Dates
2010-01-27—Published
2004-03-11—Filed