DERIVATIVES OF 2-PHENOXY AND 2-PHENYLSULPHONAMIDE WITH CCR3 ANTAGONISTIC ACTIVITY FOR TREATING ASTHMA AND OTHER INFLAMMATORY OR IMMUNOLOGICAL DISEASES Russian patent published in 2010 - IPC C07C311/37 C07D401/04 C07D241/04 C07D487/04 A61K31/18 A61K31/4965 

Abstract RU 2380356 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel derivatives of benzene sulphonamide of formula (I), tautomeric and stereoisomeric forms and physiologically acceptable salts thereof: where X is O, S; R1 is H, halogen; R2 is H, halogen; halogen; R3 is NO2, CN; R4 is: ,

where R71 is H; R72 is H; Z1 is -[CH2]P-, where p = 2.

EFFECT: compounds have antagonistic activity towards CCR3, which enables for their use in making medicinal agents.

13 cl, 1 tbl, 3 ex

Similar patents RU2380356C2

Title Year Author Number
DERIVATIVES OF PYRIMIDINE, METHOD FOR THEIR PREPARING (VARIANTS), PHARMACEUTICAL COMPOSITIONS (VARIANTS) AND INHIBITION METHOD 2001
  • Tomas Ehndrju Piter
  • N'Jukom Nikolas Dzhon
  • Khiton Dehvid Uill'Jam
RU2299201C2
2-AMINOPYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THERAPY 2001
  • Kharada Khitosi
  • Asano Osamu
  • Mijazava Sukhei
  • Ueda Masato
  • Jasuda Masakhiro
  • Jasuda Nobujuki
RU2250898C2
2,5-DISUBSTITUTED ARYLSULPHONAMIDE CCR3 ANTAGONISTS 2010
  • Laj Taj Vehj
  • Tran Mari Shantal' S'Ju-Jing
  • Baaum Ehrik Din
RU2532515C2
IMIDAQZOLO-5-YL-2-ANILINOPYRIMIDINES AS AGENTS FOR INHIBITION OF CELL PROLIFERATION, METHOD FOR THEIR PREPARING (VARIANTS), USING, PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING 2001
  • Bro Glorija Ann
  • N'Jukom Nikolas Dzhon
  • Tomas Ehndrju Piter
RU2284327C2
NEW INHIBITOR BASED ON A QUINOLINE DERIVATIVE 2019
  • Wu, Frank
  • Wan, Zhonghui
RU2802283C2
COMPOUNDS OF (2-CARBOXYAMIDO)(3-AMINO)THIOPHENE 2004
  • Uinn Grekhem Majkl
  • Dojl Kevin
  • Akhmed Salekh
  • Li An'-Khu
  • Kejli Dzhon Frejzer
  • Razamizon Kristell'
  • Pegg Nil Ehntoni
  • Saba Imaad
  • Tomas Klehr
  • Smit Don
  • Sadik Shazia
  • N'Juton Gari
  • Doson Grekhem
  • Krju Ehndrju Filip
  • Kastehlano Arlindo Lukas
RU2339633C2
NON-NUCLEOSIDE REVERSE TRANCRIPTASE INHIBITORS, USES THEREOF, PHARMACEUTICAL COMPOSITION FOR HIV INHIBITION 2004
  • Dann Dzhejms Patrik
  • Khogg Dzhoan Kheder
  • Mirzadegan Taranekh
  • Svolou Stiven
RU2305680C2
AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF 1996
  • Bro Glorija Ehnn
RU2198878C2
1,5-BENZOTHIAZEPINES AND EMPLOYMENT THEREOF AS ANTIHYPERLIPIDEMIC DRUGS 2001
  • Starke Ingemar
  • Dal'Strom Mikaehl'
  • Blomberg David
RU2302414C2
COMPOUNDS AND COMPOSITIONS AS ITPKb INHIBITORS 2007
  • Pan' Shifehn
  • Lju I
  • Si Jun'Fehn
  • Chehn Daj
  • Van' Juntsin'
  • Khan' Dun
  • Jan Jan
  • Gao Vehn'Tsi
  • Tszjan Tszitsin
  • Bursalaja Badri
  • Chamberlejn Filip
  • Karanevski Donald S.
  • Van Sja
RU2425826C2

RU 2 380 356 C2

Authors

Li Infu

Behjkon Kevin

Sugimoto Khiromi

Fukusima Keiko

Khasimoto Kentaro

Marumo Makiko

Morivaki Tosija

Nunami Noriko

Tsuno Naoki

Urbans Klaus

Esida Nagakhiro

Dates

2010-01-27Published

2004-03-11Filed