FIELD: medicine.
SUBSTANCE: invention covers compound 6-amino-4-chloropyrazolo[3,4-d]pyrimidine. Offered compound is made of 2-amino-4,6-dichloropyrimidine by the two-staged method based on a common reaction of selective replacement of hydroxyl group with chlorine atom (chlorodehydroxylation) and replacement of hydrogen atom with carbonyl group followed with ring closure of the product with hydrazine. The declared compound provides a specific inhibiting action on human 8-oxoguanine-DNA-glycosylase enzyme (hOggl).
EFFECT: low-price and available compound, extended range of specific inhibitors of said enzyme and possibility for effective application in medicine.
2 dwg, 2 ex
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