FIELD: medicine, pharmaceutics.
SUBSTANCE: medication represents derivatives of nucleotides of general formula (I)
, where X is H or OR1; one or two of substituents R1, R2, R3 are monosaccharide residues, the remaining ones are hydrogen protons; B is nitrous base bound in α- or β-position.
EFFECT: obtaining medication for inhibiting human enzyme poly(ADP-ribose)polymerase-1.
1 cl, 1 tbl, 2 dwg, 6 ex
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Authors
Dates
2011-02-20—Published
2009-10-19—Filed