FIELD: medicine.
SUBSTANCE: syphilis diagnostic technique provides the stage of serum protein fractionation with magnetic particles, mass spectrometre analysis of an eluate sample, and analysis of the derived mass spectrum for the presence or absence of a peak set corresponding to syphilis biomarkers. The presence of the characteristic peak set in the mass spectrum shows syphilis, while the absence of the characteristic peak set in the mass spectrum shows the absence of syphilis in the patient.
EFFECT: developed effective syphilis diagnostic technique in the patient by the method of direct proteomic blood serum profiling by detecting the syphilis biomarkers in the serum test sample.
2 cl, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| DIAGNOSTIC TECHNIQUE FOR AXONAL DEMYELINATING POLYNEUROPATHIES | 2010 |
|
RU2441240C1 |
| DIFFERENTIAL DIAGNOSIS METHOD FOR IDENTIFYING THE CASES OF EARLY LATENT SYPHILIS AND FALSE POSITIVE SEROLOGIC SYPHILIS TESTS | 1999 |
|
RU2157536C1 |
| SYPHILIS DIAGNOSTIC TECHNIQUE BY SIMULTANEOUS DETECTION OF REAGINIC AND TREPONEMA-SPECIFIC T PALLIDUM ANTIBODIES ON MICROSCOPE ALDEHYDE SLIDES | 2009 |
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RU2394496C1 |
| DIAGNOSTIC NEUROSYPHILIS METHOD | 2018 |
|
RU2699057C1 |
| PROTEOTYPIC PEPTIDE Q9Y4W6-02 AND METHOD OF SPECTROMETRIC ANALYSIS OF THE CONTENT OF AFG3-LIKE HUMAN PROTEIN ON ITS BASIS | 2012 |
|
RU2673551C2 |
| PROTEINS DCLK1 AND RIPK1 BIOMARKERS OF SIMPLE SCHIZOPHRENIA | 2021 |
|
RU2788149C1 |
| DIFFERENTIAL DIAGNOSIS METHOD FOR IDENTIFYING THE CASES OF EARLY LATENT SYPHILIS AND FALSE POSITIVE SEROLOGIC SYPHILIS TESTS | 1998 |
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RU2157539C2 |
| METHOD OF DIAGNOSING SYPHILIS | 1994 |
|
RU2084894C1 |
| METHOD OF DIAGNOSTICS OF KIDNEY DAMAGE IN CHILDREN WITH VESICOURETERAL REFLUX | 2023 |
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RU2814399C1 |
| METHOD FOR SERODIAGNOSTICS OF EARLY NEUROSYPHILIS | 2001 |
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RU2205409C2 |
