INDOLE DERIVATIVES AS HISTAMINE RECEPTOR ANTAGONISTS Russian patent published in 2010 - IPC C07D401/12 C07D401/14 C07D403/12 C07D403/14 C07D405/14 C07D409/14 A61K31/405 A61K31/4453 A61K31/4458 A61K31/4465 A61K31/5375 A61K31/54 A61P3/04 

Abstract RU 2382778 C2

FIELD: chemistry.

SUBSTANCE: described are compounds of formula , where X, R1, R2, R3, R4 and R5 assume values given in the description and paragraphs of the formula of invention, and their pharmaceutically acceptable salts.

EFFECT: compounds have antagonistic activity on histamine receptor 3 (H3).

25 cl, 3 tbl, 215 ex

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Authors

Makartur Silvija Gatti

Khertel' Kornelija

Nettekoven Mattias Genrikh

Raab Zuzanne

Roshe Oliv'E

Rodriges-Sarm'Ento Rosa-Marija

Shuler Frants

Planshe Zhan-Mark

Dates

2010-02-27Published

2005-06-13Filed