FIELD: medicine.
SUBSTANCE: there is offered method for chemical treatment of xenopericardium that involves chemical stabilisation of xenopericardium with 0.625% glutardialdehyde and following processing with 1% sodium dodecyl sulphate; chemically stabilised xenopericardium is additionally processed with 0.05÷0.25% aqueous solution of chitosan or metal-containing chitosan with deacetylation degree 50÷98% and molecular weight 4÷140·103 at pH 3÷5; upon termination of processing, xenopericardium is fixed in 70% aqueous solution of ethanol; then modified xenopericardium is kept in 0.10÷0.50% aqueous solution of chitosan N-sulphosuccinate with molecular weight 10÷166·103 or chitosan 3,6-O-disulphate with molecular weight 7÷180·103 at pH 4÷8 during 20÷60 mines at temperature 20÷30°C with following fixation in absolute ethanol.
EFFECT: improved durability and biocompatibility of bioprostheses.
3 ex, 7 tbl, 3 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREIMPLANTATION PREPARATION OF BIOPROSTHESES | 2007 |
|
RU2384309C2 |
| METHOD FOR MANUFACTURING BIOPROSTHESIS OF CARDIAC VALVE | 2003 |
|
RU2238061C1 |
| BIOLOGICAL CHITOSAN COATED PERICARDIAL VALVE PROSTHESIS AND METHOD FOR MAKING IT | 2012 |
|
RU2519219C1 |
| METHOD OF MAKING VALVE BIOPROTESIS OF HEART VALVE ON FLEXIBLE BASE FRAMEWORK WITH LOW PROFILE | 2017 |
|
RU2698983C2 |
| METHOD FOR TREATMENT OF HEART VALVE BIOPROTHESIS | 0 |
|
SU1651890A1 |
| METHOD OF PROCESSING GRAFTS FOR CARDIOVASCULAR SURGERY USING SUB- AND SUPERCRITICAL CARBON DIOXIDE | 2022 |
|
RU2796364C1 |
| METHOD FOR CARRYING OUT PRE-IMPLANTATION TREATMENT OF HEART VESSELS AND VALVES | 1996 |
|
RU2120212C1 |
| METHOD FOR MODIFYING BIOTISSUE FOR PROSTHETIC REPAIR | 2012 |
|
RU2523879C2 |
| BIOLOGICAL MATERIAL FOR PROSTHESES | 2009 |
|
RU2418607C1 |
| METHOD FOR PRE-IMPLANTATION TREATMENT OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2023 |
|
RU2827028C1 |
