FIELD: medicine.
SUBSTANCE: before enzymatic treatment, a biotissue is placed into a hypertonic saline and exposed to ultrasound for 20-300 minutes. That is followed by terrilytin treatment in the concentration of 0.1-10 Production Units per 1g of the tissue, washing in an acetic acid solution and sodium hydrocarbonate, keeping in multiply changed glutaric dialdehyde solutions of the increasing concentrations, and sterilisation.
EFFECT: invention ensures maintaining a collagen-elastic structure of the biotissue, reducing a degree of its mineralisation, using fewer reactants for treatment, preparing a non-immunogenic biomaterial crossed throughout.
2 cl, 3 ex
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