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2 385 939

(13)

(51)

IPC

C12N15/63(2006-01-01)

(21) (22)

Application

2008134932/13, 2008-08-29

(24)

Start date

2008-08-29

(22)

Actual filing date

2008-08-29

(45)

Published

2010-04-10

(72)

Inventor

Churikov Nikolaj AndreevichKretova Ol'Ga Valer'EvnaPokrovskij Andrej GeorgievichGashnikova Natal'Ja Matveevna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Nauk Institut Molekuljarnoj Biologii Im. V.A. Ehngel'Gardta RanFederal'Noe Agentstvo Po Nauke I Innovatsijam

GENETIC MAKERS ATTACKING SIX NEW RNA INTERFERENCE TARGETS IN TRANSCRIPTS OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 AND SUPPRESSING VIRUS REPRODUCTION IN HUMAN CELLS Russian patent published in 2010 - IPC C12N15/63

Abstract RU 2385939 C1

FIELD: medicine.

SUBSTANCE: genetic makers of siSTRIKE-neo vector producing interfering RNA (siRNA), are inhibitors of reproduction of human immunodeficiency virus type 1. Invention allows producing effective anti-HIV preparations of siRNA produced in cells by the administered genetic makers containing palindrome intended for formation of siRNA production and selected with using non-virus and virus models.

EFFECT: invention can be used in medicine and researches.

12 cl, 3 dwg, 3 tbl, 3 ex

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RU 2 385 939 C1

Authors

Churikov Nikolaj Andreevich

Kretova Ol'Ga Valer'Evna

Pokrovskij Andrej Georgievich

Gashnikova Natal'Ja Matveevna

Dates

2010-04-10—Published

2008-08-29—Filed