ALPHA-AMINOAMIDE DERIVATIVES USED FOR TREATING LOWER URINARY TRACT DISORDERS Russian patent published in 2010 - IPC C07D307/79 C07D311/20 C07D333/54 A61K31/165 A61K31/353 A61K31/343 A61K31/381 A61K31/4427 A61P13/02 A61P13/08 A61P13/10 C07D313/08 C07D335/06 A61K31/341 A61K31/277 

Abstract RU 2395504 C2

FIELD: chemistry.

SUBSTANCE: invention relates to use of a therapeutic agent which is an α-amino-amide compound of formula (I):

, in which R is a phenyl ring which is optionally substituted with one or two substitutes independently selected from halogen, hydroxy, cyano, C1-C6-alkyl, C1-C6-alkoxy or trifluoromethyl; R1 is hydrogen or C1-C6-alkyl; R2 and R3 are independently selected from hydrogen, C1-C4-alkyl; R4 and R5 independently denote hydrogen, C1-C6-alkyl; X is O or S; Y and Z, taken together with X and a phenyl ring bonded to Y and X, form a 5-7-member saturated heterocycle containing O or S atoms, or Y and Z denote hydrogen; or its isomers, mixtures and pharmaceutically acceptable salts for preparing a medicinal agent for treating lower urinary tract disorders.

EFFECT: obtaining a pharmaceutical composition based on the said compounds.

8 cl, 6 ex

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RU 2 395 504 C2

Authors

Barbanti Elena

Veneroni Orietta

Taler Florian

Pellich'Jari Roberto

Benatti Luka

Sal'Vati Patrisija

Dates

2010-07-27Published

2005-01-20Filed