METHOD OF USAGE OF (HALO BENZYLOXY)BENZYLAMINO-PROPANAMIDE FOR PRODUCTION OF MEDICATIONS WITH SELECTIVE MODULATING ACTIVITY ON SODIUM AND/OR CALCIUM CHANNELS Russian patent published in 2010 - IPC A61K31/165 A61P29/00 A61P25/06 

Abstract RU 2391973 C2

FIELD: medicine.

SUBSTANCE: invention belongs to (R)-2-[4-(2-fluorbenzyloxy)benzylamino]propanamid as individual isomer and its pharmaceutically acceptable salt, to its or (R)-2-[4-(2-chloro benzyloxy)benzylammino]-N-methylpropanamid as individual isomers or their pharmaceutically acceptable salts (the salts of methansulphonic acid are preferable) for usage in producing of medication with selective modulating activity on sodium and/or calcium channels and for this reason effective in prevention, relieving and treating of pathological processes, including pain, migraine, peripheral diseases, cardio-vascular diseases, inflammatory processes which affect all systems of organism, diseases of skin and adjacent tissues, disorders of respiratory system, immune and endocrinal systems, gastrointestinal, urogenital, metabolic and paroxysmal disorders in which mentioned above mechanisms was described as pathologic.

EFFECT: invention is free of side effect of MAO inhibition, it reduces hepatic toxicity and risk of hypertensive crisis, so on, during treatment of mentioned diseases.

25 cl, 2 tbl, 6 ex

Similar patents RU2391973C2

Title Year Author Number
3-AMINOPYRROLIDONE DERIVATIVES 2004
  • Taler Florian
  • Sabido David Chibehle Marija
  • Maehstroni Sara
  • Ravel'Ja Luka Franchesko
  • Sal'Vati Patrisija
RU2395495C2
2-PHENYLETHYLAMINO DERIVATIVES AS CALCIUM AND/OR SODIUM CHANNEL MODULATORS 2006
  • Taler Florian
  • Napoletano Mauro
  • Sabido-David Chibehle
  • Moridzhi Ehrmanno
  • Kachch'Ja Karla
  • Faravelli Laura
  • Rehstivo Alessandra
  • Sal'Vati Patrisija
RU2397160C9
CYCLOPENTYL DERIVATIVES 2004
  • Melloni P'Ero
  • Sabido David Chibehle Marija
  • Rehstivo Alessandra
  • Forlani Roberto
  • Sal'Vati Patrisija
RU2372325C2
ALPHA-AMINOAMIDE DERIVATIVES USED AS ANTIMIGRAINE AGENTS 2003
  • Sal'Vati Patrichija
  • Kalabrezi Marchello
  • Do Ljuchiano
  • Veneroni Orietta
  • Melloni P'Ero
RU2336077C2
α -AMINOAMIDE DERIVATIVES APPLICABLE AS ANTI-INFLAMMATORY AGENTS 2004
  • Sal'Vati Patrichija
  • Veneroni Orietta
  • Barbanti Elena
  • Rudzhero Far'Ello
  • Benatti Luka
RU2396251C2
N-ACYL-N' -BENZYLALYLENEDIAMNO DERIVATIVES 2004
  • Taler Florian
  • Sabido David Chibele Marija
  • Faravelli Laura
  • Gal'Jardi Stefanija
  • Kolombo Elena
  • Sal'Vati Patrichija
RU2387636C2
ALPHA-AMINOAMIDE DERIVATIVES USED FOR TREATING LOWER URINARY TRACT DISORDERS 2005
  • Barbanti Elena
  • Veneroni Orietta
  • Taler Florian
  • Pellich'Jari Roberto
  • Benatti Luka
  • Sal'Vati Patrisija
RU2395504C2
SUBSTITUTED AMINOALKYL- AND AMIDOALKYLBENZOPYRAN DERIVATIVES 2006
  • Kabotti Andzhelo
  • Melloni P'Ero
  • Taler Florian
  • Kachch'Ja Karla
  • Maehstroni Sara
  • Sal'Vati Patrisija
RU2392276C2
α-AMINOAMIDE DERIVATIVES EFFECTIVE IN TREATING RESTLESS LEGS SYNDROME AND ADDICTIVE DISORDERS 2005
  • Bezana Klaudija
  • Barbanti Elena
  • Itstso Ehmanuela
  • Taler Florian
  • Far'Ello Rudzhero
  • Sal'Vati Patrisija
  • Benatti Luka
RU2403030C2
PHARMACEUTICAL COMPOSITION CONTAINING GABAPENTIN OR ITS ANALOG AND α-AMINOAMIDE AND ITS USING AS ANALGESIC 2002
  • Sal'Vati Patrisija
  • Veneroni Or'Etta
  • Maj Roberto
  • Far'Ello Rudzhero
  • Benatti Luka
RU2295337C2

RU 2 391 973 C2

Authors

Barbanti Elena

Taler Florian

Kachch'Ja Karla

Far'Ello Rudzhero

Sal'Vati Patrichija

Dates

2010-06-20Published

2005-07-28Filed