FIELD: medicine.
SUBSTANCE: group of the inventions refers to medicine, namely to oncology, and can be used in bone cancer related pain management. The method involves administration to the patient of effective amount of a nerve growth factor (NGF) antagonist representing a NGF antibody. A set includes the NGF antagonist in the form of the NGF antibody and application instructions.
EFFECT: inventions allow for effective pain management, both constant, and motion related, due to high affinity of the NGF antibody without affecting the initial thresholds of thermal and mechanical sensitivity.
20 cl, 4 tbl, 14 dwg, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PAIN TREATMENT | 2009 |
|
RU2630969C2 |
| METHOD OF TREATMENT OF POSTOPERATIVE PAIN BY ADMINISTERING OF ANTAGONIST OF FACTOR OF GROWTH OF NERVES AND COMPOSITIONS CONTAINING FACTOR OF GROWTH OF NERVES | 2003 |
|
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| PDGFRα ANTIBODIES FOR TREATING SECONDARY BONE TUMOUR | 2006 |
|
RU2502523C2 |
| INHIBITION OF DISSEMINATION OF TUMOUR USING Bv8 OR G-CSF ANTAGONISTS | 2010 |
|
RU2567803C2 |
| PAIN TREATMENT | 2009 |
|
RU2712166C2 |
| COMPOSITION OF COMPOUNDS AND WAYS OF THEIR APPLICATION | 2015 |
|
RU2659068C1 |
| HUMAN ANTIBODIES WITH HIGH AFFINITY TO HUMAN NERVE GROWTH FACTOR | 2008 |
|
RU2473564C2 |
| METHODS AND COMPOSITIONS FOR TUSC2-IMMUNOTHERAPY | 2017 |
|
RU2755903C2 |
| METHODS OF OSTEOARTHRITIS PAIN MANAGEMENT BY ADMINISTRATION OF NERVE GROWTH FACTOR ANTAGONIST AND COMPOSITIONS CONTAINING IT | 2006 |
|
RU2429013C2 |
| NGF AND TrkA RECEPTOR BINDING INHIBITING MOLECULES AS PROLONGED ANALGESICS | 2006 |
|
RU2427387C2 |
