METHODS AND COMPOSITIONS FOR TUSC2-IMMUNOTHERAPY Russian patent published in 2021 - IPC A61K38/17 A61K39/395 A61P35/00 

Abstract RU 2755903 C2

FIELD: medicine; pharmaceutics.

SUBSTANCE: group of inventions relates to the field of medicine and pharmaceutics, namely, to a method for the treatment of a malignant neoplasm in an individual, where the method includes conducting TUSC2 therapy in an individual, where at least one immune checkpoint inhibitor has been injected or is being injected to an individual, additionally including the injection of at least one immune checkpoint inhibitor to an individual, where at least one immune checkpoint inhibitor contains an anti-PD1 antibody; to a set for the treatment of a malignant neoplasm containing a therapeutic agent TUSC2 and an immune checkpoint inhibitor, which is an anti-PD1 antibody; and to a composition for the treatment of a malignant neoplasm containing a therapeutic TUSC2 and an immune checkpoint inhibitor, which is an anti-PD1 antibody, in the amount that is therapeutically effective for the treatment of a malignant neoplasm.

EFFECT: group of inventions provides a synergetic effect in the combined therapy of malignant neoplasms.

38 cl, 40 dwg, 2 ex

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RU 2 755 903 C2

Authors

Roth, Jack, A.

Ji, Lin

Dates

2021-09-22Published

2017-10-12Filed