FIELD: biotechnology, carbohydrates. SUBSTANCE: method is carried out in a common reaction mixture using fucosyltransferase to obtain C-glycosidic bond between guanosine-5'-diphosphofucose and available hydroxyl group of carbohydrate acceptor molecule up to producing a fucosylated carbohydrate and guanosine-5'-diphosphate. Then guanosine-5'-diphosphate is recirculated to form guanosine- -5'-diphosphofucose. EFFECT: improved method of synthesis of fucosylated carbohydrates. 28 cl, 30 dwg, 8 tbl, 19 ex
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