POLYPHENOL-ENRICHED COMPOSITION EXTRACTED FROM COCOA BEAN POD Russian patent published in 2010 - IPC A61K36/185 C07C37/00 A61P39/06 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmacy. There are performed 1) provision of defatted cocoa bean pod; (2) extraction of defatted cocoa bean pod with an aqueous solution of acetone containing 30 to 80 percent of acetone, for preparing a substance of liquid cocoa bean pod extract; (3) processing the substance of liquid cocoa bean pod extract for removing suspended solid matters and preparing the substance of processed liquid cocoa bean pod extract; (4) removing acetone from the substance of processed liquid cocoa bean pod extract for preparing a substance of aqueous extract; (5) concentration of the substance of aqueous extract to the solid content 1.5 to 5 percent for preparing a substance of concentrated extract; (6) introduction of the substance of concentrated extract in a gel filtration column containing a gel filtration medium applicable for separating theobromine and polyphenols; (7) watering the gel filtration column to collect a theobromine-enriched composition, and (8) elution of the watered gel filtration column by a polar organic solvent of low molecular weight for collecting a polyphenol-enriched composition where the polyphenol-enriched composition essentially does not contain phytosterols and theobromine. The composition is prepared by the method described above.

EFFECT: invention allows implementing specified object matter.

22 cl, 2 ex, 2 dwg