FIELD: medicine.
SUBSTANCE: there is offered a method of postmedicamentous immunodeficiency assessment by single intraperitoneal introduction to experimental rats of an injection of 0.5 ml of a cytostatic agent - Cyclophosphan in dosage 4 mg/100 g of body weight; two months later there are evaluated weights of spleen (WS) and thymus (WT), leukocyte (LK) and blood lymphocyte (LP), blast-transformation reaction (BTR), spleen antibody-forming cells (AFC), leukocyte phagocytic activity (LPA) and phagocytic index (LPI). The method is characterised by the fact that an immune activity index (IAI) is calculated by formula , and if the IAI is less than 580 units, development of prolonged postmedicamentous immunodeficiency is stated.
EFFECT: method improvement.
6 ex, 1 tbl
Title | Year | Author | Number |
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|
RU2374700C1 |
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METHOD FOR PROPHYLAXIS OF IMMUNODEFICIENCY | 2005 |
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RU2301092C2 |
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RU2529694C2 |
IMMUNOMODULATION METHOD IN EXPERIMENTAL MEDICINE | 0 |
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SU1772818A1 |
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RU2445713C1 |
Authors
Dates
2010-06-27—Published
2008-08-07—Filed