METHOD FOR ESTIMATING IMMUNODEFICIENCY PROPHYLAXIS Russian patent published in 2005 - IPC

FIELD: medicine.

SUBSTANCE: method involves treating immunocompetent organ regions with low frequency electric current for instance in animal groups like rats during 2 weeks. Drug-induced immunodeficiency is modeled in the animals 2 days later, after the treatment course is over, by intraperitoneally introducing 2% cyclophosphan solution once per 3 days (the total preparation dose is equal to 42 mg). Spleen and thymus mass, antibody-forming cells quantity in spleen and phagocytic activity of leukocytes are determined. Prophylactic action of factor of physical nature is evaluated by calculating prophylaxis index by dividing product of spleen mass, antibody-forming cells and phagocytic activity of leukocytes per thymus mass. The result is to be divided by 10³. The prophylaxis index value exceeding 8.0, prophylaxis effectiveness is considered to be available.

EFFECT: high accuracy of estimates.