METHOD OF PREDICTING DEVELOPMENT OF RECURRENT INVASIVE URINARY BLADDER CANCER Russian patent published in 2010 - IPC A61B10/00 C12Q1/68 

Abstract RU 2393772 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to oncourology. DNA is isolated from peripheral venous blood erythrocytes, PCR-analysis is carried out with further restriction of amplified fragments from polymorphic locus Ile105Val of gene GSTPI. If in patients with superficial forms of UBC homozygotic genotype Val/Val is detected, high risk of development of recurrent invasive urinary bladder cancer (UBC) is predicted. If homozygotic genotype Ile/Ile is detected, minimal risk of development of recurrent UBC is predicted. Application of invention predicts risk of invasive UBC development in patients with superficial forms of UBC.

EFFECT: method ensures high accuracy of prediction.

2 ex

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RU 2 393 772 C1

Authors

Pavlov Valentin Nikolaevich

Izmajlov Adel' Al'Bertovich

Izmajlova Svetlana Mikhajlovna

Viktorova Tat'Jana Viktorovna

Galimzjanov Vitalij Zakhitovich

Kutlijarov Linat Minikhanovich

Dates

2010-07-10Published

2009-03-23Filed