FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, namely to dentistry, and can be used to predict congenital cleft lip and palate in a child when planning pregnancy in a region with ecotoxicants using genetic markers. DNA is isolated from lymphocytes of peripheral venous blood of the mother, the polymerase chain reaction method is used to amplify the polymorphic loci of the genes glutathione S-transferase M1 (GSTM1) and genaglutathione S-transferase P1 (GSTP1) using specific sequences of oligonucleotide primers.
EFFECT: improvement of prediction of congenital cleft lip.
1 cl, 2 tbl, 3 ex
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