CRF-RECEPTOR ANTAGONISTS AND TECHNIQUES RELATING TO THEM Russian patent published in 2010 - IPC C07D487/04 A61K31/519 A61P25/00 A61P25/24 C07D231/10 C07D231/38 

Abstract RU 2394035 C2

FIELD: medicine.

SUBSTANCE: invention refers to 3 - (2-methoxy-4-pyrazol-1-ilfenil) -2,5-dimethyl-7-(3-methylpyridine-2-yl) pyrazolo [1.5-a] pyrimidine or its pharmaceutically acceptable salts, solvate, stereoisomer, having the following structural formula, which are antagonists of CRF-receptors and can be used in treatment of various disorders that cause hypersecretion of CRF in warm-blooded animals, such as at the sudden attack. Also the invention refers to intermediate compounds, pharmaceutical compositions on the basis of this compound and method of treating disorder causing hypersecretion of CRF in mammals.

EFFECT: improvement of composition.

15 cl, 14 tbl, 28 ex

Similar patents RU2394035C2

Title Year Author Number
HALOGENALLILAMINE DERIVATIVES AND THEIR APPLICATIONS 2020
  • Van, Chzhunkhoj
  • Li, Lin
  • U, Frank
RU2793850C2
IAP INHIBITORS 2005
  • Koehn Frederik
  • Dezej Kurt
  • Fehjrbrozer Uehjn Dzh.
  • Fehn Bajnjan'
  • Flajgehr Dzhon
  • Gazzard L'Juis Dzh.
  • Tszui Viki Sjao-Vehj
RU2401840C2
DERIVATIVES OF BENZIMIDAZOLIDINONE AS AGENTS FOR MUSCARINIC RECEPTORS 2002
  • Kelli Nikolas Mikaehl'
  • Kok Kristian Norup
  • Tol'F Bo-Ragnar
RU2288919C2
CALPAIN MODULATORS AND THEIR THERAPEUTIC USE 2017
  • Bakmen, Bred Ouen
  • Nikolas, Dzhon Bimond
  • Yuan, Shendun
  • Adler, Mark
  • Emayan, Kumarasvami
  • Ma, Tszinyuan
RU2773288C2
AMINO-SUBSTITUTED ETHYLAMINO-AGONISTS OF β-ADRENERGIC RECEPTORS 2004
  • Linsell Martin S.
  • Dzhekobsen Dzhon R.
  • Saito Dajsuke Roland
RU2385317C2
ANTIFIBROUS PYRIDINONES 2015
  • Ramfal Dzhonni I.
  • Bakmen Bred Ouen
  • Emayan Kumarasvami
  • Nikolas Dzhon Bimond
  • Sejvert Skott D.
RU2692485C2
PRODRUGS OF OPIOID RECEPTOR ANTAGONISTS 2018
  • Shakh, Nikezh
  • Tusche, Majkl V.
  • Dzhi, Liangliang
  • Ding, Mingping
  • Khan, Tsyan
RU2785777C2
IAP INHIBITORS 2013
  • Koen Frederik
  • Gazzard Lyuis Dzh.
  • Tsuj Vikki Khsyao-Vej
  • Flajger Dzhon A.
RU2728789C2
COMPOUNDS INHIBITING (BLOCKING) BITTER TASTE, METHODS FOR USE AND PRODUCTION THEREOF 2008
  • Li Sjaodun
  • Pehtron Ehndrju
  • Tachdzhian Kehtrin
  • Sjuj Khun
  • Li Tsin
  • Pronin Aleksej
  • Servant Gaj
  • Chzhan Lan'
  • Brehdi Tomas
  • Darmokhusodo Vinsent
  • Arellano Melissa
  • Selchau Viktor
  • Ching Brett Vejlan
  • Karanevskij Donald S.
  • Brast Pol
  • Lin Tszin
  • Chzhao Vehn'
  • Prist Chad
RU2522456C2
P38 INHIBITORS AND APPLICATION METHODS 2004
  • Manson Mark
  • Mareska Dejvid A.
  • Kim Joungbu
  • Grounberg Robert
  • Ritstsi Dzhejms
  • Rodriges Marta
  • Kim Gangkhikok
  • Vajgers Gaj
  • Rao Chang
  • Balachari Devan
  • Kharvi Darren
RU2357957C2

RU 2 394 035 C2

Authors

Lo Chzhijun

Sli Debora Kh.

Tell'Ju Dzhon Ehdvard

Uill'Jams Dzhon P.

Chzhan Sjaokhu

Dates

2010-07-10Published

2004-12-20Filed