FIELD: medicine.
SUBSTANCE: claimed invention relates to cemical-pharmaceutical industry and deals with phthalide derivatives, their application in production of sensibilisers or means of reversion of anti-tumour medications. Phthalide derivatives according to claimed invention can overcome or reduce polyrestance to medications, 5-30 times enhance growth inhibition caused by chemical therapeutic medications as well as considerably promote death of tumour cells caused by medications.
EFFECT: said phthalide derivatives considerably enhance sensitivity of tumour cells irrespective of anti-tumour medication type.
10 cl, 6 ex, 6 tbl , 4 dwg
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