[N'-(ISO)QUINOLYLMETHYLENE]HYDRAZIDES OF 3-METHOXY-13,17-SECOESTRA-1,3,5(10)-TRIEN-17-OIC ACID Russian patent published in 2023 - IPC C07D215/12 C07D215/14 C07D215/18 C07D215/20 C07D215/22 C07D215/227 C07D215/26 C07D217/16 A61P35/00 

Abstract RU 2801166 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to new [N'(iso)quinolylmethylene]hydrazides 3-methoxy-13,17-secoestra-1,3,5(10)-triene-17-oic acid of the following general formula, which have antiproliferative activity against MCF-7 breast cancer cells and can be used in medicine, veterinary medicine, chemical and pharmaceutical industry and biotechnology.

R1 and R2=H, Me, OMe, Cl or F

EFFECT: obtaining [n'-(iso)quinolylmethylene]hydrazides of 3-methoxy-13,17-secoestra-1,3,5(10)-trien-17-oic acid.

2 cl, 4 tbl, 22 ex

Similar patents RU2801166C1

Title Year Author Number
SUBSTITUTED O-ALKYL-2-ARYLHYDRAZINE CARBOTIOATES AND METHOD FOR THEIR PREPARATION 2021
  • Yuskovets Valerij Nikolaevich
  • Ananeva Elena Petrovna
  • Trukhanova Yuliya Aleksandrovna
  • Chernov Nikita Maksimovich
  • Yakovlev Igor Pavlovich
RU2786442C1
SUBSTITUTED 2-METHYLIDEN-5-(PHENYLAMINO)-2,3-DIHYDROTIOPHEN-3-ONE FOR TREATMENT OF LEUKEMIAS WITH TRANSLOCATIONS OF MLL-GENE AND OTHER ONCOLOGICAL DISEASES 2017
  • Kazyulkin Denis Nikolaevich
  • Korochkina Lyubov
RU2656603C1
AGENTS ENHANCING GROWTH HORMONE SECRETION 2001
  • Martine Zhan
  • Ferents Zhan-Alehn
  • Gerlaveh Vensan
RU2270198C2
COMPOUNDS USEFUL AS TRPM8 MODULATORS 2011
  • Prist Chad
  • Nonkovich Alen
  • Petron Endryu
  • Ung Dzhejn
RU2608109C2
DERIVATIVES OF 3-AMINOMETHYLQUINOLONE-2 AS INHIBITORS OF NO-SYNTHETASE AND METHOD FOR THEIR PREPARING, BIOLOGICALLY ACTIVE COMPOUNDS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2003
  • Kirpichenok Mikhail Alekseevich
  • Genis Dmitrij Vladimirovich
  • Rodin Oleg Gennad'Evich
  • Solov'Ev Aleksandr Nikolaevich
  • Kochubej Valerij Sergeevich
  • Saekov Vladimir Nikolaevich
RU2267485C2
RACEMIC 3-HYDROXY-16-METHYL-2-FLUORO-13a-ESTRA-1,3,5(10),8(9),15-PENTAEN-17-ONE AS MEANS OF HORMONE REPLACEMENT THERAPY AND METHOD OF OBTAINING THEREOF 2013
  • Shavva Aleksandr Grigor'Evich
  • Morozkina Svetlana Nikolaevna
  • Fidarov Alan Fidarovich
  • Eshchenko Natal'Ja Dmitrievna
RU2526264C1
ANTIBACTERIAL AGENTS 1999
  • Khanter Majkl Dzhorzh
  • Bekett Rajmond Pol
  • Klements Dzhon Martin
  • Uittaker Mark
  • Dehvis Stiven Dzhon
  • Prehtt Lajza Mari
  • Spehvold Zoe Mari
  • Lounchbari Stiven
RU2246941C2
BENZAMIDE DERIVATIVES HAVING ANTICANCER ACTIVITY, METHODS FOR PRODUCTION THEREOF AND USE THEREOF 2011
  • Baj Khua
  • Chzhao Sjujjan
  • Gun Junsjan
  • Chzhun Tszin'Tsin
  • Chzhu Tsifehn
  • Lju Sjaojuj
  • Lju Lifehj
  • Chzhou Tsisjan'
RU2565079C2
NOVEL 1,2,4-TRIAZOLE COMPOUNDS, METHODS FOR THEIR PREPARING AND MEDICAMENTS CONTAINING THEREOF 2002
  • Nakamura Khiroshi
  • Kaneda Sojchi
  • Sato Takakhiro
  • Ashizava Naoki
  • Matsumoto Kozhi
  • Ivanaga Takashi
  • Inoueh Tsutomu
RU2293733C2
ANELLATED 9-HYDROXY-1,8-DIOXO-1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-7-CARBOXAMIDES - INTEGRASE INHIBITORS, METHODS FOR PREPARING AND USING THEREOF 2019
  • Ivashchenko Andrej Aleksandrovich
  • Ivashchenko Aleksandr Vasilevich
  • Mitkin Oleg Dmitrievich
  • Savchuk Nikolaj Filippovich
RU2717101C1

RU 2 801 166 C1

Authors

Ilovajskij Aleksej Igorevich

Merkulova Valentina Mikhajlovna

Chernoburova Elena Ivanovna

Shchetinina Marina Anatolevna

Zavarzin Igor Viktorovich

Terentev Aleksandr Olegovich

Shcherbakov Aleksandr Mikhajlovich

Andreeva Olga Evgenevna

Salnikova Diana Igorevna

Dates

2023-08-02Published

2023-02-09Filed