METHOD OF CORRECTING ISCHEMIC LIVER AFFECTION Russian patent published in 2010 - IPC A61K31/44 G09B23/28 A61K35/14 A61P41/00 A61P1/16 

Abstract RU 2394574 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to experimental surgery, and can be used for correction of ischemic liver affection. For this purpose 2 hours before operation 5% mexicor solution in dose 10 mg/kg of weight is intravenously jet injected to experimental animal. After that one hour before operation actovegin in dose 10 mg/kg of weight is intravenously jet injected. During operation ischemia is created by temporal extracorporal portacaval shunting. In post-operation period each of preparations is introduced 1 time a day during 7 days. Interval between their introduction is 12 hours: mexicor is introduced at 8 o'clock, actovegin - at 20 o'clock.

EFFECT: method ensures reduction of reperfusion disorders, elongation of safe terms of liver exsanguination up to 30 minutes and prevention of massive hemorrhage in operations on this organ.

3 dwg, 4 tbl, 3 ex

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RU 2 394 574 C1

Authors

Zatolokin Vasilij Danilovich

Per'Kov Andrej Alekseevich

Bezhin Aleksandr Ivanovich

Dates

2010-07-20Published

2009-05-20Filed