METHOD OF FORECASTING PROGRESS OF RESTENOSIS AFTER CORONARY ARTERIES STENTING WITH STENTS WITHOUT DRUG COATING Russian patent published in 2010 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: to predict progress of restenosis after coronary arteries stenting with stents without drug coating genotypes of polymorphisms Glu298Asp of gene endothelial nitric oxide synthase (eNOS) and gene Pro198Leu of glutathione peroxidase-1 (GPx-1) are determined in patient. While identifying only alleles Glu298 and Pro198 of polymorphisms Glu298Asp of gene eNOS and Pro198Leu of gene GPx-1 in patient, low risk of restenosis is predicted. If allele 298Asp of polymorphism Glu298Asp of gene eNOS or allele 198Leu of polymorphism Pro198Leu of gene GPx-1 are detected in genotype, average risk of restenosis is predicted. If presence of both allele 298Asp of polymorphism Glu298Asp of gene eNOS and allele 198Leu of polymorphism Pro198Leu of gene GPx-1 is detected, high risk of restenosis is predicted.

EFFECT: method provides high degree of reliability of forecasting progress of restenosis after coronary arteries stenting using stents without drug coating.

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