FIELD: chemistry.
SUBSTANCE: invention relates to granulocyte colony-stimulating factor peptide conjugates formed by linkage through an intact glycosyl linker group of (polyethylene glycol) PEG fragments. Said conjugates are obtained from glycosylated and non-glycosylated peptides under the effect of glycosyl transferase. Glycosyl transferase links a fragment of modified sugar to an amino acid or glycosyl peptide residue.
EFFECT: improved method.
35 cl, 24 dwg, 2 tbl, 6 ex
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