NANOCOATINGS FOR OSTEOINTEGRATED BIOMEDICAL PROSTHESES Russian patent published in 2010 - IPC A61L27/30 A61L27/50 A61F2/28 

FIELD: medicine.

SUBSTANCE: there are described new materials and methods for preparing a titanium dioxide coatings for osteointegrated biomedical prostheses. The invention also refers to an endosseous implant containing biologically compatible metal materials; characterised by the fact that specified implant has a coating containing a nanocrystalline material, containing nanoparticles of formula (I) AO_x-(L-Meⁿ⁺)j; (I) where AO_x represents TiO₂ or ZrO₂; Meⁿ⁺ represents metal ion exhibiting antibacterial activity, with n=1 or 2; L represents a bifunctional organic molecule which can simultaneously contact metal oxide and with metal ion Meⁿ⁺; and i represents a number of L-Meⁿ⁺ groups fixed to one AO_x nanoparticle.

EFFECT: coatings are formed by nanomaterials exhibiting antibacterial properties and provide osteointegration of implants and, at the same time, reduce rejection peculiar to inflammatory processes caused by infections which can develop next to implants.

19 cl, 1 dwg, 4 tbl