FUNCTIONAL NANOMATERIALS WITH ANTIBACTERIAL AND ANTIVIRAL ACTIVITY Russian patent published in 2010 - IPC C07F15/00 C07F5/02 C07F1/08 C07F1/10 B22F1/02 A61K31/295 A61K31/30 A61P17/00 

FIELD: medicine.

SUBSTANCE: invention refers to nanocrystalline compounds of formula (I) AO_x-(L-Meⁿ⁺)_i where AO_x represents metal oxide where A it specified from Ti or Zr, x=2; Meⁿ⁺ represents metal ion exhibiting antibacterial activity, specified from Ag⁺ and Cu⁺⁺, where n=1 or 2; L represents a bifunctional molecule, or a organic or metal-organic molecule able to get bound with metal oxide and ion metal Meⁿ⁺ simultaneously; where the organic molecule is specified from pyridine, dipyridyl, tripyridyl, functionalized with carboxylic groups (-COOH), boronic groups (-B(OH)₂), or phosphonic groups (-PO₃H₂), or 4-mercaptophenylboronic acids; where the metal-organic molecule represents a metal-organic complex containing organic ligand coordinated with central metal atom and containing boronic (-B(OH)₂), phosphonic (-PO₃H₂) or carboxylic (-COOH) functional group, and the groups are coordinated with central metal atom and able to get bound with metal ions with antibacterial activity; where specified organic ligand coordinated with central metal atom is specified from pyridine, dipyridyl, tripyridyl functionalized with carboxylic groups (-COOH), boronic groups (-B(OH)₂), or phosphonic groups (-PO₃H₂), or 4-mercaptophenylboronic acids; i represents a number of groups L-Meⁿ⁺ bound with nanoparticle AO_x. Also, there are offered a composition exhibiting antibacterial and/or antiviral activity, dermatological compositions, application of nanocrystalline compounds, a method of nanocrystalline compounds regeneration.

EFFECT: nanocrystalline compounds show effective antibacterial action.

27 cl, 4 tbl, 4 dwg