FIELD: chemistry.
SUBSTANCE: invention relates to pharmaceutical production and a rosmarinic acid synthesis method. The method for synthesis of rosmarinic acid from plant material involves extraction with water and purification. Zosteraceae sea grass is extracted with water for 6-8 hours at room temperature while adding edible acid to pH 2.5-3.0. After extraction, the obtained solution is filtered and the grass is pressed to obtain an extra extract. The extracts are combined and purified on a membrane microfilter and then on a chromatographic column with polychrome-1. The end product is eluated with 5-7% aqueous solution of ethyl alcohol, concentrated and lyophilised.
EFFECT: method is simple and ensures high output and purity of rosmarinic acid.
2 cl, 3 dwg, 3 ex
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