FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a method for preparing rosmarinic acid and can be used in pharmaceutical industry. A method involves extraction, filtration, chromatography, elution and concentration; the raw material is presented by an elevated part of plants high in rosmarinic acid in the elevated part, particularly corn mint, or side wort, or big-flowered self, or marsh woundwort or a combination thereof, and a dominating ingredient of rosmarinic acid among phenolcarboxylic acid; the plants are extracted; after the extraction, the prepared solution is filtered; the chromatography is performed in a polyamide column with by frontal chromatography; the elution is performed with 60% methanol; the concentration follows the re-crystallisation.
EFFECT: method provides extending the raw material base, provides preparing high-purity high-yield rosmarinic acid.
5 dwg, 2 tbl, 6 ex
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Authors
Dates
2015-02-20—Published
2013-06-04—Filed