METHOD OF MAKING CHROMATOGRAPHIC GENERATOR OF TECHNETIUM-99m FROM NEUTRON-IRRADIATED MOLYBDENUM-98 Russian patent published in 2010 - IPC G21G1/06 

FIELD: chemistry.

SUBSTANCE: method of making a chromatographic technetium-99m generator from neutron-irradiated molybdenum-98 involves depositing a predetermined mass of molybdenum into a chromatographic column with aluminium oxide. For this purpose, eluate output of technetium-99m from the generators with different adsorbed molybdenum mass is determined. Through extrapolation from the obtained calibration curve, the mass of molybdenum which corresponds to maximum output of technetium-99m from the generator B_e=1 is found as m_i=exp[(1-a)/b], where a and b are coefficients of the calibration curve B_i=a+b·ln m_i, where B_i is the eluate output of technetium-99m from the generator for the adsorbed mass of molybdenum m_i.

EFFECT: obtaining a generator based on neutron-irradiated molybdenum-98 with a narrow eluate profile for extracting technetium-99m.

1 cl, 3 dwg