FIELD: chemistry.
SUBSTANCE: invention relates to use of poly (ADP-ribose) polymerase inhibitors of formulae I, II and III in treating cancerous growths in cells with genetic defect of a homologous recombination mediating gene. When using compounds of formulae I, II and III, a mammal with a genetic defect of a homologous recombination mediating gene is selected first and said compounds are then used to induce opoptosis in cells with said defect
EFFECT: method of treating cancer in mammals with genetic defect of a homologous recombination mediating gene.
23 cl, 9 dwg, 1 tbl
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