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2 404 191

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IPC

C07K14/805(2006-01-01)

C07D487/22(2006-01-01)

A61K38/42(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2007125604/04, 2007-07-09

(24)

Start date

2007-07-09

(22)

Actual filing date

2007-07-09

(45)

Published

2010-11-20

(72)

Inventor

Nebol'Sin Vladimir Evgen'EvichZheltukhina Galina AleksandrovnaLobanova Tat'Jana NikolaevnaNosik Nikolaj NikolaevichNosik Dmitrij NikolaevichZheltukhin Sergej Leonidovich

(73)

Holder

Ooo

HEMIN DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, METHOD OF OBTAINING, COMPOSITION AND APPLICATION Russian patent published in 2010 - IPC C07K14/805 C07D487/22 A61K38/42 A61P31/00

Abstract RU 2404191 C2

FIELD: medicine.

SUBSTANCE: invention relates to novel hemin derivatives of general formula I

where R₁=R₂ and represent β-alanyl histamine or γ-gutamyl histamine, or β-alanyl histidine, or R₁ represents γ-gutamyl histamine; Y represents CI^-; Me represents Feⁿ⁺, where n=2, 3; and where hemin carboxyl group can be modified with methyl or other C_1-8 ether their pharmaceutically acceptable salts; method of their obtaining and pharmaceutical compositions.

EFFECT: hemin derivatives of general formula I can be used as artificial nucleases, means, possessing peroxidase activity, catalysts of methyl linoleate oxidation and disinfecting, antiseptic composition, possessing virucidal activity.

9 cl, 1 dwg, 7 tbl, 10 ex

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RU 2 404 191 C2

Authors

Nebol'Sin Vladimir Evgen'Evich

Zheltukhina Galina Aleksandrovna

Lobanova Tat'Jana Nikolaevna

Nosik Nikolaj Nikolaevich

Nosik Dmitrij Nikolaevich

Zheltukhin Sergej Leonidovich

Dates

2010-11-20—Published

2007-07-09—Filed