FIELD: chemistry.
SUBSTANCE: invention relates to novel compounds: 2-{4-[2-(N,N-diethylamino)ethoxycarbonyl]phenyl} amino-4-oxo-4-R-phenyl-2-butenoic acids of general formula: 
where R=CH3O(a); where Br (b), having analgesic activity.
EFFECT: higher analgesic effect not only compared to structural anologues, but comparison standard - analgin, as well.
3 ex, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| SUCCINATE OF N-(2,4,6-TRIMETHYLPHENYL)AMIDE 2-(BETA-N,N-DIETHYLAMINO ETHYLAMINO)-4-OXO-4-(4-METHYYLPHENYL)-2-BUTENOIC ACID | 2009 |
|
RU2428412C2 |
| N-(2-THIAZOLYL)AMIDE OF 2-(2-OXO-3-INDOLINYLIDENE)HYDRAZINO-4-OXO-4-PHENYL-2-BUTENOIC ACID HAVING ANTIBACTERIAL AND ANALGESIC ACTIVITY | 2008 |
|
RU2401837C2 |
| METHYL 4-HYDROXY-4-METHYL-6-PHENYL-2-CYANOACETYLHYDRAZONOCYCLOHEXANE-1-CARBOXYLATE EXHIBITING ANALGESIC ACTIVITY | 2010 |
|
RU2446150C2 |
| 2-(6-ARYL-4-AROYL-3-METHYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDIN-5-YL)-2-OXO-N-ARYLACETAMIDES AND METHODS FOR PRODUCTION THEREOF | 2012 |
|
RU2501800C2 |
| ETHYL 4-(5-BENZOYL-6-(4-(DIETHYLAMINO)PHENYL)-4-HYDROXY-2-THIOXOHEXAHYDROPYRIMIDIN-4-CARBOXAMINO)BENZOATE, EXHIBITING ANALGESIC AND ANTI-INFLAMMATORY ACTION | 2019 |
|
RU2717246C1 |
| N-R-AMIDES OF (Z)-2[(3-ETHOXYCARBONYL)-4,5,6,7-TETRAHYDROBENZO [b]THIEN-2-YL)AMINO]-4-PHENYL-4-OXOBUT-2-ENOIC ACIDS, HAVING ANALGESIC ACTIVITY | 2012 |
|
RU2501795C1 |
| 2-(5-ETHYL-1,3,4-THIADIAZOLYL)AMIDE OF 2-(4-BROMOPHENYL)-4-OXO-4-PHENYL-2-BUTENOIC ACID, HAVING ANALGESIC EFFECT | 2013 |
|
RU2549572C2 |
| HYDROCHLORIDE OF N-(2, 6-DIMETHYLPHENYL)AMIDE OF 2-(β-N,N-DIETHYLAMINE ETYLAMINO)-4-OXO-4-(4-ETHOXYPHENYL)-2-BUTENOIC ACID, HAVING LOCAL ANAESTHETIC ACTIVITY | 2009 |
|
RU2412159C2 |
| (Z)-4-ARYL-N-[2-(2-HYDROXYMETHYL)PHENYL]-2,4-DIOXO-3-[3-OXO-3,4-DIHYDROQUINOXALINE-2(1N)-YLIDENE]BUTANAMIDES, HAVING ANALGESIC ACTIVITY | 2019 |
|
RU2722178C1 |
| 4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | 2008 |
|
RU2389724C1 |
