FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to infectious diseases, and can be used for prediction of the risk of development of severe hemorrhagic fever with renal syndrome. DNA is recovered from lymphocytes of peripheral venous blood; PCR-analysis of CYP1A1 and GSTP1 polymorphic loci follows. If observing heterozygous genotype AG of GSTP1 gene or combined 1A2C/AG genotypes of CYP1A1 and GSTP1 genes, the high risk of development of severe HFRS is predicted.
EFFECT: invention provides a precise prediction of development of severe disease.
5 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION OF SEVERE HAEMORRHAGIC FEVER WITH RENAL SYNDROME AT EARLY STAGES OF DISEASE | 2022 |
|
RU2790962C1 |
| METHOD OF PREDICTING RISK OF INFECTIOUS ENDOCARDITIS DEVELOPMENT | 2015 |
|
RU2617060C1 |
| METHOD FOR FORECASTING THE RISK OF ERYSIPELAS DEVELOPMENT | 2018 |
|
RU2683314C1 |
| METHOD OF PREDICTING DEVELOPMENT OF COMPLICATIONS OF HEMORRHAGIC FEVER WITH RENAL SYNDROME IN EARLY PERIOD OF DISEASE | 2010 |
|
RU2433407C1 |
| METHOD FOR DETERMINATION OF GENETIC PREDISPOSITION TO INFECTIVE ENDOCARDITIS | 2016 |
|
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| METHOD FOR PREDICTING CONGENITAL CLEFT LIP AND PALATE IN A CHILD WHEN PLANNING PREGNANCY IN A REGION WITH ECOTOXICANTS USING GENETIC MARKERS | 2021 |
|
RU2760786C1 |
| METHOD OF EARLY DIAGNOSTICS OF ACUTE INFECTIOUS ENDOCARDITIS | 2017 |
|
RU2651769C1 |
| METHOD OF SEVERITY ASSESSMENT FOR HEMORRHAGIC FEVER WITH RENAL SYNDROME | 2009 |
|
RU2392858C1 |
| DIAGNOSTIC TECHNIQUE FOR PULMONARY INVOLVEMENT IN PATIENTS WITH HEMORRHAGIC FEVER AND RENAL SYNDROME | 2011 |
|
RU2461835C1 |
| METHOD FOR EVALUATING THE SEVERITY OF HEMORRHAGIC FEVER FLOW ACCOMPANIED WITH RENAL SYNDROME | 2003 |
|
RU2245552C1 |
