PYRAZOLONE DERIVATIVES Russian patent published in 2010 - IPC C07D231/22 C07D231/20 C07D231/26 C07D231/56 C07D231/54 C07D471/04 C07D487/04 C07D401/04 C07D401/06 C07D409/04 A61K31/4152 A61K31/4155 A61K31/416 A61K31/437 A61P3/10 A61P3/06 

Abstract RU 2407737 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula

and pharmaceutically acceptable salts thereof, where substitutes R1-R4 are as defined in claim 1. Said compounds have 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) enzyme inhibiting activity.

EFFECT: compounds can be used in form of a pharmaceutical composition.

15 cl, 1 tbl, 94 ex

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RU 2 407 737 C2

Authors

Amrajn Kurt

Khuntsiker Daniel'

Kun Bernd

Majveg Aleksander F.

Najdkhart Verner

Dates

2010-12-27Published

2006-08-21Filed