FIELD: medicine.
SUBSTANCE: invention aims at prediction of preterm delivery of infectious genesis. Starting with the 28th week of pregnancy, the endocervical epithelium is analysed. The real-time reverse transcription and polymerase chain reaction are used to determine the gene expression level of antimicrobial peptide β defensin 1 (HBD1) in mucous cells. It its value is lower than 25.0×103 replications of complementary DNA in relation to 10 replications of complementary DNA of actin β, preterm delivery is predicted.
EFFECT: more precise prediction of preterm delivery.
2 dwg, 5 ex
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Authors
Dates
2010-12-27—Published
2009-03-10—Filed