METHOD FOR PREDICTION OF PRETERM DELIVERY OF INFECTIOUS GENESIS Russian patent published in 2010 - IPC G01N33/48 

Abstract RU 2408014 C2

FIELD: medicine.

SUBSTANCE: invention aims at prediction of preterm delivery of infectious genesis. Starting with the 28th week of pregnancy, the endocervical epithelium is analysed. The real-time reverse transcription and polymerase chain reaction are used to determine the gene expression level of antimicrobial peptide β defensin 1 (HBD1) in mucous cells. It its value is lower than 25.0×103 replications of complementary DNA in relation to 10 replications of complementary DNA of actin β, preterm delivery is predicted.

EFFECT: more precise prediction of preterm delivery.

2 dwg, 5 ex

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RU 2 408 014 C2

Authors

Makarov Oleg Vasil'Evich

Gankovskaja Ljudmila Viktorovna

Koval'Chuk Leonid Vasil'Evich

Bakhareva Irina Viktorovna

Kuznetsov Pavel Andreevich

Gankovskaja Oksana Anatol'Evna

Kartashov Dmitrij Dmitrievich

Dates

2010-12-27Published

2009-03-10Filed