THERAPEUTIC QUINONES Russian patent published in 2011 - IPC C07C50/06 C07C50/28 C07C39/19 C07C43/215 C07C43/23 C07C46/10 A61K31/05 A61K31/09 A61K31/122 A61P35/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new polyprenylated 1,4-benzoquinones of formula 1 or formula 3 or polyprenylated 1,4-hydroquinones of formula 2 or formula 4, or to their pharmaceutically acceptable salts exhibiting anticarcinogenic activity 1, 2, 3, 4. In formulae 1-4 each of R1 and R2, irrespectively of others, can be a hydrogen radical or (C₁-C₆)-alkoxy-group; each of R3 and R4 irrespectively of others, can be a hydrogen radical or (C₁-C₆)-alkyl group; n can be equal to 2 or 3.

EFFECT: provided application of new compounds and some common 1,4-benzoqunones and 1,4-hydroqunones for preparing a drug, a based pharmaceutical composition, development of a method of oncotherapy, a method of inducing AP-1-dependent or NF-kB-independent transcription activity or both activities simultaneously in a cell and a method of inducing apoptosis in a cell, as well as separating glabruquinones.

21 cl, 3 tbl, 28 dwg, 26 ex