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2 412 187

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IPC

C07D487/04(2006-01-01)

C07D401/06(2006-01-01)

C07D403/06(2006-01-01)

C07D413/06(2006-01-01)

A61K31/4188(2006-01-01)

A61P23/00(2006-01-01)

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Application

2009129338/04, 2009-07-29

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Start date

2009-07-29

(22)

Actual filing date

2009-07-29

(45)

Published

2011-02-20

(72)

Inventor

Anisimova Vera AlekseevnaSpasov Aleksandr AlekseevichGrechko Olesja Jur'EvnaEliseeva Natal'Ja VladimirovnaTolpygin Ivan Evgen'EvichMinkin Vladimir Isaakovich

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Federal'Nyj Universitet"Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet" Vpo Volgmu)

SALTS OF 9-(2-MORPHOLINOETHYL)-2-(4-FLUOROPHENYL)IMIDAZO [1,2-a]BENZIMIDAZOLE AND SALTS OF 9-AMINOETHYL-SUBSTITUTED -(4-FLUOROPHENYL)IMIDAZO [1,2-a]BENZIMIDAZOLE, HAVING ANALGESIC ACTION Russian patent published in 2011 - IPC C07D487/04 C07D401/06 C07D403/06 C07D413/06 A61K31/4188 A61P23/00

Abstract RU 2412187 C1

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds of the 2,9-disubstituted imidazo[1,2-a]benzimidazole family, specifically to water-soluble salts of 9-aminoethyl-substituted 2-(4-fluorophenyl)imidazo[1,2-a]benzimidazole of general formula I:

where NR² = pyrrolidine-, piperidine-, morpholine-; Y=HBr, H₂SO₄, (CH₂COOH)₂ and [CH(OH)COOH]₂; n=1, 2.

EFFECT: novel compounds have analgesic action.

2 cl, 2 tbl, 15 ex

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RU 2 412 187 C1

Authors

Anisimova Vera Alekseevna

Spasov Aleksandr Alekseevich

Grechko Olesja Jur'Evna

Eliseeva Natal'Ja Vladimirovna

Tolpygin Ivan Evgen'Evich

Minkin Vladimir Isaakovich

Dates

2011-02-20—Published

2009-07-29—Filed