FIELD: chemistry.
SUBSTANCE: invention relates to a method for synthesis of 5-(4-oxo-2-thioxo-1,3,4,5-tetrahydro-2H-chromeno [2,3-d] pyrimidin-5-yl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione of formula
, which involves reaction of thiobarbituric acid with salicylic aldehyde in ethyl alcohol medium with molar ratio of reagents equal to 1:1 at temperature 70-80°C for 30 minutes.
EFFECT: novel method for synthesis of said compounds with high output, which can be used as a intermediate product for preparing medicinal agents for treating Alzheimer's disease.
1 cl, 1 ex
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