TRI-SUBSTITUTED AMINE COMPOUNDS AND THEIR APPLICATION AS INHIBITORS OF CHOLESTEROL ESTER TRANSFER PROTEIN (CETP) Russian patent published in 2011 - IPC C07D239/46 C07D239/48 C07D401/04 C07D401/12 C07D403/12 C07D413/04 C07D413/12 A61K31/505 A61P3/06 

Abstract RU 2412937 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to compounds of general formula (I-B), where values of radicals are described in formula of invention, or to its pharmaceutically acceptable salts, which possess activity of inhibiting cholesterol ester transfer protein, due to which said compounds or salts can be used for prevention and/or treatment of arteriosclerotic diseases, hyperlipemia or dislipidemia or similar diseases.

EFFECT: obtaining pharmaceutical compositions for prevention and treatment of arteriosclerosis, as well as application of formula I-B compounds for manufacturing of medication.

15 cl, 36 tbl, 252 ex

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RU 2 412 937 C2

Authors

Nakamura Josinori

Khajasi Norimitsu

Khigasidzima Takanori

Kubota Khitosi

Oka Kozo

Dates

2011-02-27Published

2007-01-30Filed