METHOD FOR MAKING SERUM FOR DIAGNOSING BOVINE Q FEVER IN INDIRECT IMMUNOFLUORESCENCE TEST Russian patent published in 2011 - IPC A61K39/395 

Abstract RU 2413533 C2

FIELD: medicine, veterinary science.

SUBSTANCE: invention refers to veterinary science. A method involves hyperimmunisation of rabbits with an antigen with scheduled introduction of the immune-stimulating agent levamizole in the first and fourth day of hyperimmunisation, dynamic studying of antibody synthesis on the 7th, 14th, 21st and 30th days, exsanguination of the rabbits and production of serum. Antigen is vaccine strain C.burnetii M-44 inactivated by heating +70° for 30 minutes.

EFFECT: method allows producing Q fever serum with a high diagnostic antibody titres, as well as increasing diagnostic accuracy in bovine Q fever.

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RU 2 413 533 C2

Authors

Krasikov Aleksandr Panteleevich

Nakonechnyj Oleg Igorevich

Rudakov Nikolaj Viktorovich

Dates

2011-03-10Published

2009-05-26Filed