FIELD: medicine, veterinary science.
SUBSTANCE: invention refers to veterinary science. A method involves hyperimmunisation of rabbits with an antigen with scheduled introduction of the immune-stimulating agent levamizole in the first and fourth day of hyperimmunisation, dynamic studying of antibody synthesis on the 7th, 14th, 21st and 30th days, exsanguination of the rabbits and production of serum. Antigen is vaccine strain C.burnetii M-44 inactivated by heating +70° for 30 minutes.
EFFECT: method allows producing Q fever serum with a high diagnostic antibody titres, as well as increasing diagnostic accuracy in bovine Q fever.
5 tbl
Title | Year | Author | Number |
---|---|---|---|
METHOD OF OBTAINING MYCOPLASMOSIS DIAGNOSTIC SERUMS FOR INDIRECT IMMUNOFLUORESCENCE REACTION BY RABBIT HYPERIMMUNISATION | 2007 |
|
RU2355422C1 |
SERUM COLLECTION METHOD FOR DIAGNOSTICS OF ANAPLASMOSIS OF CATTLE IN REACTION OF INDIRECT IMMUNOFLUORESCENCE BY MEANS OF HYPERIMMUNISATION OF RABBITS | 2007 |
|
RU2368393C2 |
METHOD OF OBTAINING ERYTHROCYTE DIAGNOSTICUM FOR REACTION OF INDIRECT HEMAGGLUTINATION IN CATTLE COCCIELLOSIS | 2009 |
|
RU2410698C1 |
METHOD FOR PRODUCING A SET OF FLUORESCENT RICKETTSIAL AND QUERY FEVER DIAGNOSTICUMS AND USE THEREOF FOR SEROLOGICAL DIAGNOSIS OF RICKETTSIOSIS AND QUERY FEVER, A SEROLOGICAL DIAGNOSTIC TECHNIQUE | 2019 |
|
RU2728340C1 |
METHOD OF PERFORMING AN IMMUNOFLUORESCENCE REACTION FOR DIAGNOSING BOVINE LEUKEMIA | 2023 |
|
RU2810589C1 |
METHOD FOR PREPARATION OF DIAGNOSTIC SERUM | 1991 |
|
RU2010577C1 |
METHOD FOR DIAGNOSING RADIATION INJURIES OF ORGANISM AND PROCESS FOR PRODUCING PREPARATION | 1997 |
|
RU2145712C1 |
METHOD FOR HUMAN VACCINATION AGAINST INFLUENZA | 0 |
|
SU1686368A1 |
METHOD OF PRODUCING HYPERIMMUNE SERUM AGAINST CATTLE PARAINFLUENZA-3 | 2015 |
|
RU2587323C1 |
METHOD FOR PRODUCTION OF ERYTHROCYTIC DIAGNOSTICUM FOR INDIRECT HEMAGGLUTINATION REACTION IN CATTLE MYCOPLASMOSIS | 2007 |
|
RU2342155C1 |
Authors
Dates
2011-03-10—Published
2009-05-26—Filed