PYRAZOLOPYRIMIDINE DERIVATIVES AS CYCLIN-DEPENDENT KINASE INHIBITORS Russian patent published in 2011 - IPC C07D487/04 A61K31/519 A61P35/00 A61P35/02 

Abstract RU 2414472 C9

FIELD: chemistry.

SUBSTANCE: invention relates to novel 5,7-diamino-substituted pyrazolo[1,5-a]pyrimidines selected from specific compounds, e.g. those given below, which have cyclin-dependent kinase inhibiting properties, such as CDK2. The compounds can be used to treat diseases and conditions associated with CDK, such as proliferative diseases, leukaemia.

.

EFFECT: more effective use of the compounds.

12 cl, 87 tbl, 1057 ex

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RU 2 414 472 C9

Authors

Gutsi Timoti Dzh.

Pehrakh Kehmil

Dvajer Majkl P.

Doll Ronal'D Dzh.

Girijavallabkhan Vijur Mupil

Mehllems Alan

Al'Vares Karmen S.

Kirtikar Kartik M.

Rivera Dzhojslin

Chan Tin-Jau

Mehdison Vinsent

Fishmann T'Erri O.

Dillard Lourens V.

Trehn Vin D.

Khi Zhen Min

Dzhejms Rehj Ehntoni

Park Khehngsun

Paradkar Vidijadkhar M.

Khobbs Duglas Uolsh

Dates

2011-03-20Published

2005-02-08Filed