FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to new compounds described by formula 
in which radical and symbol values are specified in the patent claim, and their pharmaceutically acceptable salts. These compounds inhibit tompomyosine-related kinases (Trk), and can find application in treating a malignant growth, such as breast cancer, rectal cancer and prostate cancer. Also, the invention relates to a method for producing these compounds, a based pharmaceutical composition and to methods of application thereof.
EFFECT: preparation of the pharmaceutical composition which can find application in treating a malignant growth.
18 cl, 134 ex
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