NOVEL SALT I Russian patent published in 2011 - IPC C07D211/58 A61K31/4468 A61P11/06 

Abstract RU 2417220 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound which is N-{2-[((2S)-3-{[1-(4-chlorobenzyl)piperidin-4-yl]amino}-2-hydroxy-2-methylpropyl)oxy]-4-hydroxyphenyl}acetamide benzoate or solvate thereof. The invention also relates to a pharmaceutical composition, dry inhalant powder, use of compounds in any of claims 1-6, as well as a method of modulating chemokine receptor 1 (CCR1).

EFFECT: obtaining a novel biologically active compound, having chemokine receptor 1 (CCR1) modulating activity.

13 cl, 6 ex, 2 tbl, 4 dwg

Similar patents RU2417220C2

Title Year Author Number
COMBINATION OF COMPOUNDS, WHICH CAN BE APPLIED IN TREATMENT OF RESPIRATORY DISEASES, ESPECIALLY CHRONICAL OBSTRUCTIVE LUNG DISEASE (COLD) AND ASTHMA 2006
  • Ehriksson Tomas
  • Khansson Jokhan
RU2414222C2
DERIVATIVES OF PIPERIDINE, METHODS FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2001
  • Ehriksson Tomas
  • Klingstedt Tomas
  • Mussi Tesfaledet
RU2298550C2
NOVEL COMPOUNDS 2001
  • Ehriksson Tomas
  • Klingstedt Tomas
  • Mussi Tesfaledet
RU2419608C2
DERIVATIVES OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHODS FOR TREATMENT OF INFLAMMATORY DISEASES AND RESPIRATORY WAYS DISEASES 2001
  • Bodkin Majkl
  • Ehriksson Tomas
  • Khansen Peter
  • Khemmerling Martin
  • Khenriksson Krister
  • Klingstedt Tomas
  • Pettersson Lars
RU2265011C2
DERIVATIVES OF 1'-(2-HYDROXY-3-ARYLOXYPROPYL-1-YL)-SUBSTITUTED SPIRO[BENZOFURAN-PIPERIDINES], SPIRO[BENZOFURAN-PYRROLIDINES] AND SPIRO[CHROMEN-PIPERIDINES], METHOD FOR THEIR PREPARING, INTERMEDIATE COMPOUND AND METHOD FOR ITS PREPARING, PHARMACEUTICAL COMPOSITION, USING 2003
  • Khossain Nafizal'
  • Ivanova Svetlana
  • Monsonides-Kharsema Margerite
RU2320664C2
COMBINATIONS CONTAINING ANTIMUSCARINIC AGENTS AND INHIBITORS PDE4 2005
  • Gras Ehskardo Khordi
  • Llenas Kal'Vo Khesus
  • Rajder Khamish
  • Orvis Dias Pio
RU2404772C2
METHODS OF USING THIAZOL DERIVATIVES 2007
  • Molfino Nestor A
  • Saito Kosuke
  • Nagamoto Khisasi
RU2542502C2
TOSYLATE SALT OF 5-PYRAZOLYL-2-PYRIDONE DERIVATIVE EFFECTIVE IN COPD TREATMENT 2010
  • Al'Karaz Mari-Lin
  • Briggner Lars-Ehrik
  • Klingstedt Per Tomas
  • Lenn Khans Roland
  • Niklasson Khelena
  • Nikson Robert Ehntoni
  • Uotts Ehndrju Dzhejms
  • Zuban Robert
RU2526038C2
COMBINATIONS CONTAINING ANTIMUSCARINIC AGENTS AND PDE4 INHIBITORS 2005
  • Gras Ehskardo Khordi
  • Llenas Kal'Vo Khesus
  • Rajder Khehmish
  • Orvis Dias Pio
RU2373935C2
DERIVATIVES OF CHROMONE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION 1996
  • D-R Andreas Fon Shprekher
  • D-R Mark Gershpakher
  • D-R Robert Man
  • D-R Sil'Vio Roggo
  • D-R Val'Ter Shilling
  • D-R Sil'Vio Ofner
  • D-R Sim Jakob Veenstra
RU2156250C2

RU 2 417 220 C2

Authors

Dzhovannini Zhjul'En

Josefsson Bo-Jeran

Dates

2011-04-27Published

2006-07-31Filed