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(19)

(11)

2 417 984

(13)

(51)

IPC

C07D209/52(2006-01-01)

C07D221/22(2006-01-01)

C07D401/06(2006-01-01)

C07D401/12(2006-01-01)

C07D403/06(2006-01-01)

C07D405/06(2006-01-01)

C07D405/12(2006-01-01)

C07D413/06(2006-01-01)

A61K31/403(2006-01-01)

A61K31/439(2006-01-01)

A61K31/4439(2006-01-01)

A61K31/5355(2006-01-01)

A61K31/541(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2009140115/04, 2008-03-27

(24)

Start date

2008-03-27

(22)

Actual filing date

2008-03-27

(45)

Published

2011-05-10

(72)

Inventor

Khehmmond Filip S.Mazurov Anatolij A.Sjao Jun'-DehMerti Srinivasa V.Akireddi Srinivasa Rao

(73)

Holder

Targasept, Ink.

RECEPTOR SUBTYPE-SELECTIVE AZABICYCLOALKANE DERIVATIVES Russian patent published in 2011 - IPC C07D209/52 C07D221/22 C07D401/06 C07D401/12 C07D403/06 C07D405/06 C07D405/12 C07D413/06 A61K31/403 A61K31/439 A61K31/4439 A61K31/5355 A61K31/541 A61P25/00

Abstract RU 2417984 C1

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds which are methyl-3-azabicyclo[3.3.0]octane-7-carboxylate, N-methyl-3-azabicyclo[3.3.1]nonane-7-carboxamide, N-propyl-3-azabicyclo[3.3.1]nonane-7-carboxamide, or pharmaceutically acceptable salts thereof. The invention also relates to compounds selected from a group, a pharmaceutical composition, methods of treating or preventing central nervous system disorders, as well as use of compounds in any of claims 1-4.

EFFECT: obtaining novel biologically active compounds having activity on neural nicotinic acetylcholine receptor.

11 cl, 14 ex, 7 tbl, 2 dwg

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RU 2 417 984 C1

Authors

Khehmmond Filip S.

Mazurov Anatolij A.

Sjao Jun'-Deh

Merti Srinivasa V.

Akireddi Srinivasa Rao

Dates

2011-05-10—Published

2008-03-27—Filed