FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed are monophase pharmaceutical composition, containing conjugated estrogen and hydrophilic or lipophilic excipient, where conjugated estrogen includes sodium estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17β-dihydroequilin sulfate, sodium 17α-estradiol sulfate, 17β-estradiol sulfate, sodium equilenine sulfate, sodium 17α-dihydroequilenine sulfate and sodium 17β-dihydroequilenine sulfate, where viscosity constitutes more than approximately 1 poise and less than approximately 30000 poise, containing single dose of said composition applicator, set of applicators and corresponding method of treating conditions in menopause.
EFFECT: increase of diffusion and flowing of estragens from claimed pharmaceutical compositions in comparison with premarin cream.
51 cl, 10 dwg, 8 tbl, 9 ex
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