FIELD: chemistry.
SUBSTANCE: group of inventions relates to chemistry of high-molecular compounds and a three-dimensional porous composite material and a method for production thereof. Three-dimensional porous composite material is characterized by that it contains a composite frame having a chitosan salt as a polymer matrix and a paired polymer selected from collagen or chondroitin sulphate or chitin. Method of producing three-dimensional porous composite material is characterized by dissolving chitosan in aqueous acid solution, adding collagen, or chondroitin sulphate, or chitin. After homogenous system is obtained, while mixing, foaming agent is added, which is represented by either sodium bicarbonate, or potassium bicarbonate or ammonium bicarbonate, washing the sample to neutral pH and drying. Composite material can be used as components of bone scaffolds, frame for tissue regeneration in vitro and / or in vivo, frames for tissue regeneration, replacement of defects of bone tissue, hemostatic materials, wound coatings, matrices for tissue engineering.
EFFECT: group of inventions improves osteoconductivity, porosity, strength and biodegradability of the composite material.
5 cl, 3 tbl, 6 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING CHITOSAN SPONGE (VERSIONS) | 2018 |
|
RU2700693C1 |
| METHOD FOR PRODUCING MINERALIZED COMPOSITE MICROSCAFFOLDS FOR BONE TISSUE REGENERATION | 2016 |
|
RU2660558C2 |
| COMPOSITION OF BIORESORBABLE 3D MATRIX FOR RESTORING BONE TISSUE DEFECTS | 2021 |
|
RU2762511C1 |
| HYDROGEL BIOCOMPOSITE BASED ON BACTERIAL POLYSACCHARIDES FOR USE IN TISSUE ENGINEERING | 2023 |
|
RU2819701C1 |
| REGENERATIVE MATERIAL OF CONNECTIVE TISSUES, METHOD FOR OBTAINING REGENERATIVE MATERIAL, USE OF REGENERATIVE MATERIAL, IMPLANT | 2018 |
|
RU2788658C2 |
| SOLUTION FOR PREPARING CHITOSAN MATERIAL, METHOD FOR PREPARING HAEMOSTATIC MATERIAL OF THIS SOLUTION (VERSIONS) AND MEDICAL DEVICE WITH USING CHITOSAN FIBRES | 2011 |
|
RU2487701C2 |
| BIOCOMPATIBLE BIODEGRADABLE SCAFFOLD BASED ON POLYMER COMPOSITE CONTAINING HYDROXYAPATITE NANOPARTICLES | 2019 |
|
RU2756551C2 |
| METHOD FOR PRODUCTION OF HEMOSTATIC POROUS COMPOSITE MATERIAL | 2021 |
|
RU2789327C1 |
| IMPLANT FOR BONE REGENERATION AND METHOD FOR PRODUCTION THEREOF | 2017 |
|
RU2692578C1 |
| METHOD OF PRODUCING BIOCOMPATIBLE BIODEGRADABLE POROUS COMPOSITE MATERIAL | 2014 |
|
RU2568919C1 |
