NOVEL COMPOSITIONS OF VACCINES Russian patent published in 2011 - IPC A61K39/02 A61P31/04 

Abstract RU 2422155 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to biotechnologies and represents immunogenic composition - emulsion of type "oil-in-water", which contains water solution, containing antigen or immunogen, nonionogenic lipophilic ethoxylated C9-C22 alcohol of fatty series, ethoxylated 1-4 EO, mineral oil, which contains linear or branched carbon chain, which contains from 15 to 32 atoms of carbon, nonionic hydrophilic surface-active substance, which represents ethoxylated C9-C22 alcohol from fatty series, ethoxylated 5-21 EO. Total concentration of surface-active substances (by weight per volume of emulsion) constitutes from 0.2% to 6.5%, concentration of oil phase, which includes oil(s) and surface-active substances constitutes from 2% to 50% and temperature of phase inversion (PIT) constitutes from 25°C to 65°C.

EFFECT: invention can be applied as adjuvant.

19 cl, 5 tbl, 11 ex

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RU 2 422 155 C2

Authors

Parizo Aleksis Gi Andre

Deguj-Bleshe Stefani Mari-Katrin

Sharer Katrin

Rule Klod Zhan Mari

Dates

2011-06-27Published

2006-04-13Filed